The curse that William Shakespeare had engraved on his tomb ("Good frend for Jesus sake forebeare,/ To digg the dust encloased heare./ Bleste be ye man yt spares thes stones,/ And curst be he yt moves my bones.") actually worked.
Philip Schwyzer, a senior lecturer at Exeter University, said: "Shakespeare had an unusual obsession with burial and a fear of exhumation. The stern inscription on the slab has been at least partially responsible for the fact that there have been no successful projects to open the grave."
Anxiety about the mistreatment or exhumation of corpses is found in at least 16 of his 37 plays, with this concern often being more pronounced than the fear of death itself. [Link]